UPDATE: M55 closed eastbound and delays mounting following multi-vehicle pile-up
The crash happened at junction 3 near Kirkham at around 4.30pm. The road remains closed between junction 3 and junction 4, near Wesham.
The AA Roadwatch said: "Callers report that there are several vehicles stranded on both the exit slip road and main carriageway, not helped by poor weather conditions."
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Hide AdLancashire police said: "The eastbound carriageway of the M55 is currently closed at junction 3 due to a road traffic collision. Please avoid the area if possible and expect delays."
A detour is now in operation along the A583. Severe delays between the M55 junction 4 and junction 1 near Fulwood have been reported.